ABBOTT Determine™ TB LAM Ag
The Determine™ TB LAM Ag test empowers you, at the point-of-care, to screen for active TB in HIV positive patients, providing results in just minutes. This rapid test detects the LAM antigen (lipoarabinomannan) in urine samples, assisting you in your TB screening to rule-in sooner than traditional methods and enabling earlier treatment for your patient.
- Results in 25 minutes
- Convenient urine sample
Uses unprocessed urine as the validated sample type.
- Detect Pulmonary and Extrapulmonary TB
Urine is a convenient sample that is able to diagnose both pulmonary and extrapulmonary TB. HIV- infected patients often have a higher prevalence of extrapulmonary TB, which is difficult to diagnose from a sputum sample.
- Antigen Detection Test
An antigen (Ag) detection test that detects the LAM antigen. The World Health Organisation recommends against using TB antibody test as they can adversely impact patient safety.
- TB LAM Antigen
LAM is a structurally important compoinnent if the outer cell wall of mycobacteria. It is a 17.5 kDa glycolipid found at the surface of the cell.
- Best performance in immunosuppressed patients
Sputum smear microscopy perform poorly in these patients, with sensitivity decreasing as the CD4 cell count drops. In contrast, the TB LAM Ag test offers the greatest sensitivity when compares to smear microscopy in the sickest patients.